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Welcome ICBS2018 Keynote Speakers

     

Dr. Craig Crews, Yale University

“PROTAC-mediated Protein Degradation: Making Problem Proteins Go Away”

 

Dr. Jörn Piel, ETH Zürich

"New enzyme tools from uncharted natural product space"

Dr. Crews is the Lewis Cullman Professor of Molecular, Cellular and Developmental Biology and holds joint appointments in the departments of Chemistry and Pharmacology at Yale University.  He graduated from the U.Virginia with a B.A. in Chemistry and received his Ph.D. from Harvard University in Biochemistry. Dr. Crews has a foothold in both the academic and biotech arenas; on the faculty at Yale since 1995, his laboratory pioneered the use of small molecules to control intracellular protein levels. In 2003, he co-founded Proteolix, whose proteasome inhibitor, Kyprolis™ received FDA approval for the treatment of multiple myeloma.  Since Proteolix’s purchase by Onyx Pharmaceuticals in 2009, Dr. Crews has focused on a new ‘induced protein degradation’ drug development technology, PROTACs, which served as the founding IP for his latest New Haven-based biotech venture, Arvinas, LLC.  Currently, Dr. Crews serves on several editorial boards and is an Editor of Cell Chemical Biology.  In addition, he has received numerous awards and honors, including the 2013 CURE Entrepreneur of the Year Award, 2014 Ehrlich Award for Medicinal Chemistry, 2015 Yale Cancer Center Translational Research Prize, a NIH R35 Outstanding Investigator Award (2015) and the 2017 AACR Award for Outstanding Achievement in Chemistry in Cancer Research.   Jörn Piel received a PhD in Chemistry at the University of Bonn, Germany, and conducted postdoctoral work with Bradley Moore and Heinz Floss at the University of Washington, Seattle. He then became Research Group Leader at the Max Planck Institute of Chemical Ecology in Jena, Germany, and Associate Professor of Bioorganic Chemistry at the University of Bonn. Since 2013 he is Full Professor of Microbiology at ETH Zurich. Research of his lab focuses on metabolic functions of "microbial dark matter", the investigation and utilization of new biosynthetic enzymology, and ecology- and genome-based methods of natural product discovery.


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ICBS Young Chemical Biologist Awards

To advance the career development of young investigators in chemical biology, the ICBS has established a special session at the Annual Meeting to showcase up-and-coming chemical biology scientists. The selected recipients give a podium presentation during a special “Rising Stars” session. Click here to nominate a colleague.

 

Click here to see past recipients.
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9/24/2018 » 9/27/2018
ICBS2018

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