The ICBS Symposium: Chemical Biology and Drug Discovery is a one-day scientific conference attended by an audience of scientists with interdisciplinary expertise working in the field of drug discovery seeking an exchange of new information in chemical biology, technology, assays, and advances in the field of high throughput biology towards development of and application chemical probes in drug discovery. This symposium will follow the training workshop held on the nearby Pfizer campus offered by NCATS on Assay Guidance Manual (AGM) designed to share best practices and advice on assay design as used in drug discovery.