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ICBS 2018 Preliminary Agenda
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ICBS Trainee Symposium  Day  Affiliation Title
Jonathan Baell Mon Professor, Monash University PAINS and Nuisance Compounds: Sorting the Wheat From the Chaff in Bioactive Compounds 
Doug Auld Mon Sr. Investigator, Novartis Institute for Biomedical Research Considerations in the Design and Interpretation of Assays Applied to Drug Ddiscovery
Scott Lovell Mon  Director, Protein Structure Laboratory, University of Kansas Gene to Structure: Utilizing X-Ray Crystallography to Support Chemical Biology
Andrew Zhang Mon  Associate Principal Scientist, AstraZeneca Chemical Biology in Industry: Small Molecule Driven Target Deconvolution Strategies
Trainee Presentations Day Affiliation Title
Kun Qian Mon Emory University Chemical Probe Discovery to Interrogate YAP-TEAD Interaction in The Hippo Signaling Pathway
Eline Sybesma Mon Eindhoven University of Technology Disulfide Trapping for the Identification of Selective PPI Stabilizers
Ali Nejatie Mon Simon Fraser University Synthesis of biological probes
Philip Danby Mon University of British Columbia Glycosyl vs Allylic Cations in Spontaneous and Enzymatic Hydrolysis
Michael Winzker Mon Max Planck Institute of Molecular Physiology  Proteolysis targeting chimera (PROTAC) – A new tool in Drug Discovery
Sebastian Andrei Mon Eindhoven University of Technology Rational Design of Semi-synthetic Natural Product 14-3-3 PPI Stabilizers 
Karson Kump Mon University of Michigan Targeting Mcl-1 to Overcome Resistance in Solid Tumors
Oluwafemi Akintola Mon Simon Fraser Univeristy Allylic Carbasugars as Substrates for Glycoside Hydrolases
Elena Reckzeh Mon Max Planck Institute of Molecular Physiology Thermal Proteomic Profiling for Target Identification
Thomas Garner Mon Albert Einstein College of Medicine Small-molecule Inhibition of Pro-apoptotic BAX Through a Novel Site
ICBS 2018 Main Conference Day Session Title
Craig M. Crews Mon Keynote PROTAC-mediated Protein Degradation: Making Problem Proteins Go Away
Shaomeng Wang Tue Degradomics TBA
Ting Han
  Anti-cancer Sulfonamides Target Splicing by Inducing RBM39 Degradation Via Recruitment to the DCAF15 Ubiquitin Ligase Receptor
J.B. Brown Tue Computational Chemical Biology - Big Data Active Learning of Ligand-Target Interactions to Build Minimally Complex Yet Maximally Predictive Interaction
Albert Antolin
  Probe Miner: Objective, Quantitative, Data-Driven Assessment Of Chemical Probes
Barbara Mroczkowski Tue  Open Panel Session Industry/Academic Partnerships to Promote Drug Discovery Through Chemical Biology 
David Vocadlo Tue  GlycoBiology Development of Ultra-Sensitive Fret-Quenched Substrates for Quantitative Imaging of Glycoside Hydrolases in Living Cells
Jennifer Kohler
  Discovering Host Cell Receptors for Bacterial Toxins Using Photocrosslinking Sugars
Sally-Ann Poulsen Tue  Emerging Topics Development of Chemical Probes for Visualising DNA Synthesis in Complex Cellular Systems
Milka Kostic
  Chemical Probes – Re-Thinking our Ecosystem
Steve Haggarty Wed  iPSC Chemical Biology TBA
Anne Bang
  Phenotypic Screening of Human Induced Pluripotent Stem Cell Derived Neurons: Balancing Throughput With Relevance
Jason Micklefield Wed Synthetic Biology Diversification of Natural and Non-Natural Products Using Engineered Biosynthetic Pathways and Enzymes
Michelle Chang
Kaity Ryan
  Building Non-proteinogenic Amino Acids 
Scott Wolkenberg Wed The Chemical Biology - Medicinal Chemistry Continuum TBA
Rima Al-Awar
  Discovery And Optimization of OICR9429, a WDR5 Chemical Probe
David Lupton Thu Synthetic Chemistry New Reactivity, New Structures...New Functions?
Dawei Ma
  New Strategies for Synthesizing Bioactive Alkaloids 
Jin Zhang Thu Biosensors and Imaging A Suite of New Fluorescent Biosensors for Dynamic Visualization of Cell Signaling in Living Cells 
Robert Campbell
  New Colours and Applications of Genetically Encoded Biosensors to Probe Cell Signaling
Jörn Piel Thu Keynote New Enzyme Tools From Uncharted Natural Product Space 
Paul Clemons Thu Open Panel Discussion Target Identification and Mechanism-of-Action Studies in Chemical Biology
Andrew Zhang Thu Chemical Proteomics for Drug Target Engagement Elucidating PARP Inhibitor Selectivity Using a PARP Family Affinity Matrix 
Sherry Niessen
  Applying Chemical Biology in the T790M-EGFR Program
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